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In recent years, research into prions has progressed at an impressive pace. In this book internationally renowned experts provide an up-to-date description of the great advances made in our understanding of prions and prion diseases. This volume provides a comprehensive overview of the pathogenesis, molecular biology, biochemistry, cellular biology, animal biology, animal models and immunology. This book is essential to all researchers working in this highly topical field and is recommended reading for scientists in other areas of biology and medicine.